MECHANICAL SEALS FOR THE CHEMICAL INDUSTRY
Pharmaceutical
Product purity. Process reliability.
John Crane 是全球公认的为制药厂设计、制造和供应解决方案的领先者。我们的技术测试中心代表了业界最先进的开发设施。为了保持 ISO 9001:2008 认证，我们使用元件分析工具（CSTEDY 和 CTRANS）来测试我们的组件，这些工具可模拟真实条件下的密封面行为。
通过严格的测试和持续的改进，我们设计了许多行业专用组件，优化了性能、效率和可靠性。其中一些组件解决了特定的流体处理问题，而另一些组件则采用非接触式螺旋槽升离技术来减少摩擦、磨损和污染。我们的许多产品甚至可以 100％ 遏制逸散性排放，而且我们在全球拥有 200 多个快速响应服务中心，可随时提供服务、支持和维修。
John Crane solutions for the pharmaceutical industry
Mechanical seal and support systems and filtration technologies specifically designed to maintain hygiene, reduce contamination risk and improve equipment reliability in demanding process conditions.
Vessel, mixer and agitator seals
Hygienic mechanical seals designed for high purity applications in mixers, agitators, filter dryers, thin film evaporators and de foaming units.
Type CK, Type 7800 and Type 5280 seal families are engineered for glass, steel and special alloy vessels. Balanced seal faces and high performance materials support reliable operation, while non contacting designs help minimise wear and reduce contamination risk. All designs meet FDA, ISO, DIN and ATEX requirements.
More about our vessel, mixer and agitator seals
Cartridge seals
High-performance cartridge seals built for standard pumping applications where low emissions, reliability and ease of use are critical.
Manufactured from regulatory-compliant materials, these seals support safer operation, simplified installation and plant-wide standardisation.
The Type 5600 universal cartridge seal family covers a wide range of pharmaceutical duties, helping reduce downtime, improve efficiency and lower maintenance costs.
Single, dual, split, metal bellows and O-ring configurations are available.
More about our cartridge seals
Pump seals
Advanced pump sealing solutions engineered for processes requiring the highest levels of contamination control.
Non-contacting pump gas seals use an inert gas lubricant to help protect product integrity and the external environment during demanding CIP and SIP cycles.
The Type 2800 delivers virtually zero process contamination for small bore rotating equipment, while the Type 2800E pressurised dual-cartridge design provides full containment even in the event of barrier gas pressure loss.
More about our pump seals
Metal bellows
Metal bellows seals for extreme temperatures, high pressures and aggressive chemical media where a cleanable seal profile is essential.
Formed and edge welded bellows options, including the Type GL1B, Type 515E, Type 515H, Type 604, Type 609, Type 680, Type 670 and Type 676, deliver reliable sealing across a wide range of services.
More about our metal bellow seals
Seal support systems
Seal support systems engineered to maintain cleanliness, stability and reliability in critical pharmaceutical services.
Barrier fluid reservoirs, heat exchangers, gas supply panels and flush systems provide stable lubrication and cooling while reducing containment risk.
Integrated instrumentation enables monitoring of seal and system performance, and gas panels supply clean, inert lubrication to help prevent liquid contamination.
Systems can be supplied to meet ASME VIII, ASME B31.3, AD2000, ATEX, CE, PED and SELO requirements.
More about our seal support systems
Filtration
Our filtration solutions support product purity, hygiene and process reliability throughout pharmaceutical operations.
John Crane Seebach® fully welded cylindrical CIP filter elements feature a star shaped geometry and corrosion resistant construction to support automated cleaning, including repeated CIP cycles.
Filter cones and baskets are designed to retain contaminants effectively while reducing the risk of bacterial growth. A wide range of filtration options is available, with fineness down to 0.2 microns for gases and 2 microns for liquids.
More about our filtration solutions
SUSTAINABILITY
Supporting your sustainability journey in pharmaceutical processing
Today, we are leveraging our legacy of resource efficiency, emissions reduction and circularity to help our customers achieve their mission-critical sustainability goals – without sacrificing the reliability that earned us the industry’s trust more than a century ago.
Our commitment to sustainabilityJohn Crane Performance Plus™
John Crane Performance Plus™ is our modular service framework, supported by the largest mechanical seal service network, with over 200 manufacturing, sales and service centres globally. That means we are where you need us, when you need us – empowering people, plant and performance.
Common questions
Why is sealing critical in pharmaceutical manufacturing?
Sealing plays a key role in protecting product quality, maintaining hygienic conditions and supporting reliable equipment operation. Drawing on decades of applied engineering experience, John Crane helps manage leakage risks and reduce contamination potential to support processing across fluid-handling systems.
What should pharmaceutical companies look for in a sealing partner?
Pharmaceutical companies benefit from a sealing partner with strong engineering experience and global support capability. John Crane works closely with pharmaceutical processors to deliver application-specific sealing technologies backed by testing and service support throughout the equipment lifecycle.
How is sealing technology evolving in the pharmaceutical industry?
Sealing technologies continue to evolve to address increasing demands for efficiency, reliability and contamination control. John Crane develops pharmaceutical sealing solutions through ongoing investment in materials, non-contacting designs and testing methods that support continuous processing environments.
